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- CreatorI. Marlene KingStarsTroian BellisarioAshley BensonLucy HaleFour friends band together against an anonymous foe who threatens to reveal their darkest secrets, while also investigating the disappearance of their best friend.
- CreatorJenji KohanStarsTaylor SchillingDanielle BrooksTaryn ManningConvicted of a decade-old crime of transporting drug money, ordinarily law-abiding Piper Chapman is sentenced to 18 months behind bars and quickly discovers the realities of life-changing prison time.
- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny Teller moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorSteven LevitanChristopher LloydStarsEd O'NeillSofía VergaraJulie BowenThree different, but related, families face trials and tribulations in their own uniquely comedic ways.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorJames Manos Jr.StarsMichael C. HallJennifer CarpenterDavid ZayasHe's smart. He's lovable. He's Dexter Morgan, America's favorite serial killer, who spends his days solving crimes and nights committing them.
- CreatorLeila GersteinStarsRachel BilsonJaime KingCress WilliamsNew Yorker and new doctor Zoe Hart accepts an offer from a stranger, Dr. Harley Wilkes, to work in his medical practice in Bluebell, Alabama. She arrives to find that he has died and left half the practice to her in his will.
- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- CreatorJennie Snyder UrmanStarsGina RodriguezAndrea NavedoYael GrobglasA young, devout Catholic woman discovers that she was accidentally artificially inseminated.
- CreatorDavid HoldenStarsEmily OsmentJonathan SadowskiAimee CarreroA well-off young tech entrepreneur hires a feisty young food blogger to be his personal chef.
- CreatorBradley BredewegPeter PaigeStarsTeri PoloSherri SaumHayden ByerlyTeenager Callie Jacob is placed in a foster home with a lesbian couple and their blend of biological, adoptive, and foster children.
- CreatorJustin SpitzerStarsBen FeldmanLauren AshColton DunnA look at the lives of employees at a big box store.
- CreatorDaniel ChunStarsJohn StamosPaget BrewsterJosh PeckA confirmed bachelor discovers he's a dad--and a grandfather.
- CreatorIlana GlazerAbbi JacobsonStarsIlana GlazerAbbi JacobsonHannibal BuressBroad City follows two women throughout their daily lives in New York City, making the smallest and mundane events hysterical and disturbing to watch all at the same time.
- CreatorLucia AnielloPaul W. DownsIlana GlazerStarsIlana GlazerPaul W. DownsKevin HeffernanCenters on two cousins who discover a time-traveling bong and ride high as they blaze through time.
- CreatorSam BobrickStarsMark-Paul GosselaarMario LopezDustin DiamondA close-knit group of six friends get through their teens together while attending Bayside High School in Palisades, California.
- CreatorAnne HecheChad KultgenStarsKate WalshTone BellJohn DuceyA hard-living, sexually unapologetic woman plays with the law, and her life on the edge is constantly in balance as she also happens to be a judge in the Criminal Court system.
- CreatorK.J. SteinbergStarsAlyssa MilanoJes MacallanRochelle AytesFollows the scandalous lives of a group of four girlfriends, each on her own path to self-discovery as they brave the turbulent journey together.
- CreatorMarc CherryStarsAna OrtizDania RamirezRoselyn SanchezFour Latina maids with ambition and dreams of their own work for the rich and famous in Beverly Hills.
- CreatorBreckin MeyerStarsDanny MastersonMichael CassidyAdam BuschComedy following the misadventures of four buddies who work together at a magazine.
- CreatorMark BrazillBonnie TurnerTerry TurnerStarsTopher GraceLaura PreponMila KunisA comedy revolving around a group of teenage friends, their mishaps, and their coming of age, set in 1970s Wisconsin.
- CreatorJustin HalpernPatrick SchumackerStarsChristopher MeloniRachael HarrisConnor BuckleyA boy becomes a man, and a man becomes a father, in a time before coming of age was something you could Google.