Retired Old West gunslinger William Munny reluctantly takes on one last job, with the help of his old partner Ned Logan and a young man, The "Schofield Kid."
A small-time rancher agrees to hold a captured outlaw who's awaiting a train to go to court in Yuma. A battle of wills ensues as the outlaw tries to psych out the rancher.
On the run after murdering a man, accountant William Blake encounters a strange Native American man named Nobody who prepares him for his journey into the spiritual world.