A small-time crook, hunted by the authorities for a car theft and the murder a police officer, attempts to persuade a hip American journalism student to run away with him to Italy.
An angel tires of his purely ethereal life of merely overseeing the human activity of Berlin's residents, and longs for the tangible joys of physical existence when he falls in love with a mortal.
After a car wreck on Mulholland Drive renders a woman amnesiac, she and a Hollywood-hopeful search for clues and answers across Los Angeles in a twisting venture beyond dreams and reality.