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- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorSteven LevitanChristopher LloydStarsEd O'NeillSofía VergaraJulie BowenThree different, but related, families face trials and tribulations in their own uniquely comedic ways.
- CreatorMark GatissSteven MoffatStarsBenedict CumberbatchMartin FreemanUna StubbsThe quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
- CreatorFrank DarabontStarsAndrew LincolnNorman ReedusMelissa McBrideSheriff Deputy Rick Grimes wakes up from a coma to learn the world is in ruins and must lead a group of survivors to stay alive.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorDan HarmonStarsJoel McHaleDanny PudiDonald GloverA suspended lawyer is forced to enroll in a community college with an eccentric staff and student body.
- CreatorSeth MacFarlaneDavid ZuckermanStarsAlex BorsteinSeth MacFarlaneSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- StarsChris O'DowdRichard AyoadeKatherine ParkinsonThe comedic misadventures of Roy, Moss and their grifting supervisor Jen, a rag-tag team of IT support workers at a large corporation headed by a hotheaded yuppie.
- StarsSimon BirdJames BuckleyBlake HarrisonFollows four friends and their antics during their final years of school.
- StarsJohn CleesePrunella ScalesAndrew SachsHotel owner Basil Fawlty's incompetence, short fuse, and arrogance form a combination that ensures accidents and trouble are never far away.
- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorVince GilliganStarsBryan CranstonAaron PaulAnna GunnA chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- CreatorDavid ChaseStarsJames GandolfiniLorraine BraccoEdie FalcoNew Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- StarsKevin SmithWalter FlanaganMike ZapcicAn unscripted series set in Smith's iconic comic shop Jay and Silent Bob's Secret Stash and captures the world of the neighborhood comic book store and fanboy culture.
- CreatorDavid BenioffD.B. WeissStarsEmilia ClarkePeter DinklageKit HaringtonNine noble families fight for control over the lands of Westeros, while an ancient enemy returns after being dormant for millennia.
- CreatorJon BokenkampStarsJames SpaderMegan BooneDiego KlattenhoffA new FBI profiler, Elizabeth Keen, has her entire life uprooted when a mysterious criminal, Raymond Reddington, who has eluded capture for decades, turns himself in and insists on speaking only to her.
- CreatorBruno HellerStarsBen McKenzieJada Pinkett SmithDonal LogueThe story behind Detective James Gordon's rise to prominence in Gotham City in the years before Batman's arrival.
- CreatorPhillip IscoveAlex KurtzmanRoberto OrciStarsTom MisonLyndie GreenwoodNicole BeharieIchabod Crane is resurrected and pulled two and a half centuries through time to unravel a mystery that dates all the way back to the founding fathers.
- CreatorMatthew MillerStarsIoan GruffuddAlana De La GarzaJoel David MooreDr Henry Morgan, a medical examiner, works with his partner Detective Jo Martinez, to solve criminal cases. Along the way, he tries to uncover the mystery to his 200-year-old immortality.
- CreatorDavid E. KelleyStarsJames SpaderWilliam ShatnerCandice BergenBoston Legal is a spin-off of the long-running David E. Kelley series The Practice (1997), following the exploits of former Practice character Alan Shore (James Spader) at the legal firm of Crane, Poole, and Schmidt.
- CreatorTim KringStarsJack ColemanHayden PanettiereMilo VentimigliaCommon people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- CreatorLoren BouchardJim DauteriveStarsH. Jon BenjaminDan MintzEugene MirmanBob Belcher runs a struggling burger shop with his wife and three children.
- CreatorJeff EastinStarsMatt BomerTim DeKayWillie GarsonA white-collar criminal agrees to help the FBI catch other white-collar criminals using his expertise as an art and securities thief, counterfeiter, and conman.