- Niamh is pronounced Neeve
- Sister of Paul Cusack, Sinéad Cusack, Sorcha Cusack and Pádraig Cusack; half-sister of Catherine Cusack.
- Sister-in-law of Jeremy Irons.
- Has her own theatre at a school in Macclesfield, Cheshire - the Niamh Cusack Theatre opened in April 2002, a local theatre school use it to do their productions
- Daughter of Cyril Cusack and Maureen Cusack.
- Lives in London and Gloucestershire with husband actor Finbar Lynch and their son Calam Lynch.
- Originated the role of Siobhán in the stage production of " The Curious Incident of a Dog in the Night-time" at the National Theatre in London, later transferring with it to the West End in 2013. The production won six Olivier Awards. (August 2012)
- Aunt of Samuel Irons.
- Currently filming a role in Fallen Angel (2007) for ITV1 (adapted from a crime novel trilogy called "The Roth Trilogy") with Charles Dance and Emilia Fox. (July 2006)
- Currently rehearsing as part of the Ensemble in Women, Power & Politics, a series of new plays by Rebecca Lenkiewicz, 'Marie Jones', Moira Buffini, Lucy Kirkwood, Joy Wilkinson, Bola Agbaje, Zinnie Harris, Sam Holcroft and Sue Townsend. It is playing at the Tricycle Theatre in London from 4 June to 17 July and is directed by 'Indhu Rubasingham'. (May 2010)
- Appearing as "Catherine Dickens" in "Andersen's English", a new play by 'Sebastian Barry', directed by Max Stafford-Clark. The tour started in February at Theatre Royal, Bury St Edmunds, and continued to Nuffield Theatre, Southampton; West Yorkshire Playhouse, Leeds; Library Theatre, Manchester; Belgrade Theatre, Coventry; Salisbury Playhouse; and Clywd Theatre Cymru, Mold. The tour finishes in London at the Hampstead Theatre. (March 2010)
- In 2003, ran the London Marathon, fundraising for St Joseph's Hospice in East London.
- She has worked extensively in theatre including being a member of the Royal Shakespeare Company (now an Associate Artist), the National Theatre of Great Britain, the Abbey Theatre Dublin as well as several productions in London's West End.
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