- Played a total of 13 years in the National Football League (NFL) with three teams: the New York Giants, San Francisco 49ers, and Denver Broncos.
- Graduate of Central Catholic High School in Allentown, Pennsylvania. Alumni of Stanford University with a BA degree in Economics and a MA degree in Organizational Behavior.
- One of the most popular players in the history of the Denver Broncos franchise, he retired at the conclusion of the 2003 season, having endured two severe concussions and a broken leg in his final three seasons.
- Founded the McCaffrey Family Foundation, which strives to improve the lives of children, particularly within the State of Colorado.
- 1996 Ed Block Courage Award Winner, 1999 Phil Simms Iron Man Award.
- Father of Christian McCaffrey.
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