Only one scene was not shot at the University of Vermont, either on campus property or in campus buildings.
The character Professor Cadigan is a reference to author Pat Cadigan.
The fraternity Theta Chi is mentioned at one point. There is no chapter at the University of Vermont; the director heard about it when he accidentally downloaded the chapter's anthem off the Internet.
The "cheesy horror movie" the characters are watching, which we only hear, is actually a project the director made in high school.