(at around 19 mins) Harvey Stephens, who portrayed Damien in The Omen (1976), appeared in this remake as the tabloid reporter who asks Robert Thorn (Liev Schreiber) if the deceased nanny "was on drugs".
This movie was released to coincide with the date of 06/06/06 in order to spark interest and gain publicity.
(at around 33 mins) In Damien's bedroom, the wallpaper is a floral vine design curved in such a way as to make a wall of sixes.
During filming, Seamus Davey-Fitzpatrick was never told that his character was supposed to be the son of the Devil. Julia Stiles has commented that it was because the filmmakers thought "he was too young to understand it, but he was really obedient when (producer and director) John (Moore) asked him for the Damien face."
The studio originally wanted this movie to receive a PG-13 rating, but producer and director John Moore insisted on an R-rating, suggesting people would "smell a cop-out" if a remake of The Omen (1976) was to receive a family-friendly certificate.