Two minutes into the episode, as Sam is handing out the trivia napkins, KLOS Los Angeles radio personalities Mark and Brian are sitting at the end of the bar. They can be seen later, as well.
This was the final "Cheers" episode to air on Thanksgiving.
Carla refers to Quincy M.E. (1976). This was a popular slightly off-beat crime show about a medical examiner.
This is a direct nod to a classic TV comedy episode, Lucy Does a TV Commercial (1952), in which Lucy stars in a commercial for the health drink "Vitameatavegamin." The original episode is considered to be one of the greatest in television history.