While this series had its share of elderly guest stars playing the main character, Eddie Albert has the distinction of being the oldest main guest star of any episode for this series. Although his character is 74, he was actually 80 when this episode was filmed. Amazingly though he would live on another 19 years.
J. Edward McKinley's last performance.
The rare amino acid disorder may have been PKU but testing for that disease at birth became mandatory in 1966.
This is the second show of the series to take on the topic of Big Pharma.
The act of Congress mentioned in this show is the Orphan Drug Act of 1983.