The house used for the Farley Granger and Lee Grant characters' house was the same as that used as the home of Jonathan and Jennifer Hart eleven years later in Hart to Hart.
The title comes from the biblical expression: "Eat, drink and be merry" (Luke 12:19, KJV).
Guest star Richard Anderson appeared in the role of Lt. Steve Drumm in the final season of Raymond Burr's series Perry Mason (1957).
Ironside refers to the fact that in the past doctors successfully used small doses of strychnine to treat alcoholics by causing an aversion to alcohol.