George is unaware of Fred's sexual orientation because the plot of the movie "Breakfast at Tiffany's" was significantly altered to include a romantic relationship between the protagonist, Holly Golightly, and the novella's unnamed narrator, whose homosexuality is implied: in addition to calling him Fred, the name of her brother, Holly calls him "Maude," shorthand for "gay" in the 1950s.
Carl tells Elaine something like "one day we'll get enough justices on the Supreme Court" to overturn Roe, which did actually happen in 2022 with Dobbs.
The "Make you own pizza pie" idea was previously brought up by Kramer in the season 1 episode, Male Unbonding.