This pilot was animated in Flash, unlike the rest of the series, which has been animated in Animo.
Dr. Girlfriend was voiced by Christopher McCulloch instead of Doc Hammer, who provides her voice for the rest of the series.
Several differences in the Monarch can be seen in this episode compared to later episodes. The uniforms of both him and his henchmen are the easiest to spot. But his eyebrows are black in this episode, compared to red in the rest of the series.
This episode aired in February 2003 on Cartoon Network's Adult Swim.