The big painting shown a few times on the wall of the discotheque is a copy of a painting by H.R. Giger, the Swiss artist who designed Alien (1979).
First episode to be directed by Rob Bowman. He would go on to direct 33 more episodes in the series and of course was also handed the plum assignment of directing the first feature film, The X Files (1998).
Steveston is a real town located in Richmond, British Columbia and also doubles as Storybrooke, Maine in Once Upon a Time (2011). In fact, the popular Granny's Diner (Cannery Cafe in real life and as seen in this episode) is first spotted behind Mulder and Scully at 9:32.
The X Files has often been compared to the movie The Silence of the Lambs. Brent Hinkley (Brother Andrew) played Officer Murray in the movie.