Toad appears, but he doesn't speak.
Mr. and Mrs. President are based upon George Bush and Barbara Bush. who were the President and First Lady of the United States at the time this show originally aired.
Some of the background music used in this episode is slightly different in terms of instruments and pitch compared to the other episodes in the series.
This episode and Sneaky Lying Cheating Giant Ninja Koopas are the only two episodes that use classical music in the series.