Though they appeared in the opening titles of the previous episode, this is the first episode to feature Willow, Gus or Amity.
The title is an allusion to the 1957 film "I Was a Teenage Werewolf".
When Willow is first introduced, she is being picked on by Amity, causing Luz to sympathize with her. This is likely a reference to 'Buffy the Vampire Slayer,' which also featured a character named Willow who is first introduced while being picked on by a more popular girl, causing the hero to sympathize with her.