This episode's director, Greg Yaitanes, won an Emmy for "Outstanding Directing For A Drama Series." He later became a regular director on the show, and by the end of it, he had directed the most episodes.
At the end of the episode, Thirteen's name is revealed, for the first time, to be Dr. Hadley.
The bartender is played by Fred Durst, who is the lead singer/frontman for the band Limp Bizkit.
House is in his bathroom talking to his team on the phone with a nurse outside his door, and he talks about his "large colon." Although there is no such thing as the "large colon." The colon is another term for the large intestine; he likely mixed up the words.