The character of Anemone, a mermaid, is voiced by Sirenetta Leoni - whose name means "little mermaid" in Italian.
While waiting at the Bait and Repair shop, the song that Guybrush whistles is Largo's Theme from Monkey Island 2: LeChuck's Revenge (1991).
The books that can be borrowed from the Spinner Cay library are all sea-themed puns on existing book titles or sayings. 'A City of Two Tails' (originally 'A Tale of Two Cities'), 'The Old Man and the Sea Gull' ('The Old Man ans the Sea'), 'The Motion of the Ocean' (a metaphor for being a good lover), and '101 Fish Jokes' (spoofs the '101 Jokes' books).