Rose Marie Dewitt and Ron Livingston are married in real life.
At around 17 mins David Duchovny (Richard) greets Anna Faris (Savanna) and Toni Collette (Macey) saying "Whassup?". The greeting originated in a USA Budweiser commercial but became globally popular from its first mainstream parody in Scary Movie (2000), Anna's breakout movie.
David Duchovny plays Kathleen Turner's nephew, but is only six years her junior in real life.
Reunites Toni Collette with Rosemarie DeWitt after the TV series United States of Tara (2009) and The Staircase (2022). The three times they play sisters.