Shia LaBeouf became Catholic because of the film.
The filming locations are places Padre Pio lived or visited.
Padre Pio's spiritual advisor in the film is a real Capuchin Franciscan.
As a result of Shia LaBeouf's conversion, he was interviewed while filming. It is on YouTube entitled "Enlighten."
Shia LaBeouf slept and filmed in Padre Pio's bedroom.