- A man is brought in by an infertility doctor to supply him with his sperm, where he becomes the biggest sperm donor for his clinic.
- Dr. Baldev Chaddha (Anu Kapoor), a well qualified fertility expert, runs a fertility clinic and a sperm bank in Dariyaganj, New Delhi, that guarantees a high quality and specialized sperm for the purpose. Unfortunately he has more failed cases to his credit than successes. A healthy, high performing donor is the need of the hour. Vicky Arora (Ayushmann Khurrana), a young, good-looking, Punjabi boy from Lajpat Nagar, is the only son and of no financial support to Dolly, a widow, who runs a small beauty parlor from home. As luck would have it, a small brawl in the colony brings Dr Chaddha and Vicky, face to face, where Chaddha, concludes that Vicky could be THAT donor he has been looking for. From here on, Chaddha's days and nights are spent in convincing Vicky to become a donor till he finally gives in. Vicky finds his love interest in Ashima Roy (Yami Gautam), a pretty Bengali girl, who works in a Bank. But soon there hunky dory world comes crashing down because of Vicky's past as a donor. With a brief emotional roller coaster ride, Vicky Donor is a light-hearted take on the subject of sperm donation.—Official site
- The story is about Dr. Baldev Chaddha (Annu Kapoor), a fertility expert, who runs a fertility clinic and a sperm bank in Daryaganj, Delhi, that guarantees high quality and specialized sperm for the couples without issue. Unfortunately, he has more failed cases to his credit than successes. A healthy and high-performing donor is therefore need of the hour. While searching for his 'Indian Alexander', Chaddha bumps into Vicky Arora (Ayushmann Khurrana). Vicky is the only son of his widowed mother Dolly (Dolly Ahluwalia), who runs a small parlor from their home in Lajpat Nagar. He provides no financial support to her.
A small brawl in the colony brings Chaddha and Vicky face to face, where Chaddha concludes that Vicky could be the donor he has been looking for. Vicky is under pressure to join his uncle's cloth shop in Delhi. But Vicky has dreams to do a proper white collar job, a dream that his hard working mother does not support, as she sees no skills in Vicky that can help him get a job.
From here on, Chaddha's days and nights are spent in convincing Vicky to become a donor until he finally gives in. Vicky meets Ashima in a bank where he goes to open a new bank account to deposit money from his mother's beauty parlor business. Vicky then pursues Ashima at the wedding ceremony of his friend. His friends wife is Ashima's colleague at the bank where she works. Ashima rejects all of Vicky's advances. Her colleagues at the bank advise Vicky to have fun & to at least have a good meeting with Vicky to get to know him better.
Vicky is very skeptical of Baldev's plans to help childless couples to conceive using his sperm. But he is left wide eyed with all the gifts he receives from successful couples. He agrees to keep donating sperm to help more couples to conceive. Vicky quickly becomes very rich. He quickly upgrades his house & his mom's beauty parlor. Slowly Vicky & Ashima come close to each other & eventually Ashima agrees to go out on a date with Vicky. Vicky falls in love with Ashima Roy (Yami Gautam), a Bengali who works in a bank. Ashima tells Vicky that she is a divorcee, but Vicky is completely fine with it.
Despite initial rivalry between Vicky and Ashima's families due to conflicting cultures, they eventually convince their families and get happily married. It is discovered in the progress that Ashima is infertile and Vicky, with a heavy heart, takes better care of her. Soon their world comes crashing down because of Vicky's past as a sperm donor, which Ashima can not digest. Upon knowing this Dr. Baldev takes it upon him to reconcile the separated couple by holding a reunion of parents who had kids from Vicky's sperm. Ashima eventually realizes that Vicky's gift to all those couples was much greater than her own disgust with Vicky being a sperm donor and they are reconciled. They go on to adopt a child conceived of Vicky's sperm but whose parents have died in a road accident.
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