Dr. Leekie (Matt Frewer) tells Cosima (Tatiana Maslany) and Delphine (Evelyne Brochu) that they can be the next Watson and Crick of science. James Watson and Francis Crick were molecular biologists who discovered the structure of DNA in 1953, based on the work of Rosalind Franklin. Watson and Crick were awarded the Nobel Prize in Physiology or Medicine in 1962 for this discovery; Franklin was not included.
Sarah (Tatiana Maslany) tells Felix (Jordan Gavaris) that Cosima is blinded by science after meeting Delphine (Evelyne Brochu) and Dr. Leekie (Matt Frewer). This is a reference to the Thomas Dolby song "She Blinded Me with Science."
The Restaurant Helena & Sarah eat at is Jim's restaurant on Queen St In Toronto Canada it has since been Permanently Closed.