The title is a reference to the 2007 film "The Assassination of Jesse James by the Coward Robert Ford".
At the beginning of the episode, agents Dick and Jackson are seen playing three rounds of "Rock, Paper, Scissors" next to Stan before the meeting starts. Jackson wins all three times.
When Stan and Bullock walk up the driveway to the Costner mansion , you can see props of the movies that Kevin Costner has appeared in the background. 'Dances with Wolves'(1990), 'Waterworld(1993) and 'Field of Dreams '(1988) sets can be seen.
When Bullock and Stan are acting as dogs, Stan does his signature Brian dog bark.
Bullock's line about beating breast cancer was meant as a joke, but actually men can get breast cancer. About 1% of cases in the US every year are men.