Thom tracks down a man who has a right arm bigger than his left; then he sets another man the ultimate challenge: to extinguish a fire using the water in his stomach.
Thom meets Gabriel Dechichi who solves Rubik's cubes whilst blindfolded, and Derek Paravacini who can memorize an entire piece of music after a single hearing.
His quest for people with anatomical differences leads Thom to Annalisa, who has the world's loudest shout, and to Brad Byers, who has the ability to force metal objects up his nose.
On this leg of the search for unique physiological gifts, Thom meets a man capable of squirting liquid from his tear ducts and a man who claims to have heatproof hands.
Thom meets a man whose ability is to submerge his body in ice without succumbing to the effects of cold. Plus, he meets a man who developed a form of martial art to make him indestructible.
In Las Vegas, Thom meets Rick Smith Junior, a person who can turn an ordinary playing card into a lethal weapon; Brian Jackson uses his unique lung power to blow up water bottles.