During the flashback showing June Harris/ Dr Zoe Smith / Jessica Harris as a young woman on the boat with her mother and her sister the real Jessica the woman playing her mother was Angela Cartwright , the original Penny Robinson.
During the flashback when June Harris steals the identity of Dr Zacharia Smith, 15:13, the photo on the ID is of Bill Mumy, who played Will Robinson in the original Lost In Space series.
The Resolute's identification number is 6121916. June 12, 1916 is Lost in Space creator Irwin Allen's birth date. 6/12/1916.
Judy's birth father's last name is Kelly. There were three real life astronauts with the last name Kelly.
When changing the Resolute's database to her new identity, she notes the real Dr. Smith is a pediatrician. Bill Mumy, who plays the real Dr. Smith, is married to a childbirth instructor.