| 11:29 PM | Saturday Night Live: Olympic swimmer Michael Phelps hosts; Lil Wayne performs; Tina Fey as Gov. Sarah Palin. |
| 1:03 AM | Local Programming |
| 1:33 AM | Access Hollywood: The hottest entertainment news of the week. |
| 2:03 AM | Poker After Dark: Jay Heimowitz; Howard Lederer; Mickey Appleman; Dan Harrington; Steve Zolotnow; Mike Shichtman. |
| 3:02 AM | Strikeforce on NBC: Mixed martial arts competition. |
| 3:30 AM | Access Hollywood: The hottest entertainment news of the week. |
| 4:30 AM | EXTRA |
| 5:30 AM | Hispanics Today: Clarinetist Ricardo Morales; car-dealership owner Irma Elder; El Charro Cafe in Tucson, Ariz. |
| 6:00 AM | Local Programming |
| 9:00 AM | Today: Career advice for tough economic times; preparing the house for winter. |
| 10:00 AM | The Chris Matthews Show: Last weeks before Election Day and the economic crisis. |
| 10:30 AM | Meet the Press: Jon Corzine and Rob Portman discuss the financial crisis. |
| 11:30 AM | Wall Street Journal Report With Maria Bartiromo: Former Secretary of Treasury Lawrence Summers; investor Jim Rogers. |
| 12:00 PM | Access Hollywood: The hottest entertainment news of the week. |
| 1:00 PM | Local Programming |
| 2:00 PM | EXTRA |
| 3:00 PM | Lyons & Bailes Reel Talk: Singer Alicia Keys; ``Body of Lies''; ``RocknRolla''; ``City of Ember.'' |
| 3:30 PM | Houses For $300 |
| 4:00 PM | Local Programming |
| 6:30 PM | NBC Nightly News: The latest world and national news. |
| 7:00 PM | Football Night in America: With Bob Costas, Cris Collinsworth, Jerome Bettis and Tiki Barber. |
| 8:15 PM | NFL Football - New England Patriots at San Diego Chargers |
| 11:30 PM | Local Programming |