Somewhere between "Yuck!" and "Yuk-Yuk!" falls "Osmosis Jones," a puzzling but memorable departure for the Farrelly brothers, whose previous forays into bodily functions have heretofore been WAAAY beyond PG and animated only in the sense that they were vividly and hilariously grotesque.
The title character is voiced with patent hip by Chris Rock, who brings life to a white blood cell/loose cannon cop on the trail of a particularly nasty baddy named Thrax (Lawrence Fishburne). Fishburne dips an octave or two below the tones of his "Matrix" alter ego and delivers real power as the virus out to destroy the "city" of Frank (Bill Murray), who is to hygiene and nutrition what Gary Condit is to truth and justice.
A cold capsule named Drix (David Hyde Pierce) and Frank's Mayor Phlegmming (William Shatner) likewise add to a cast that fairly clicks with hammish appeal, and the animation is top drawer, particularly when Thrax happens upon Frank's subconscious. What lacks is deeper imbedding into Frank's infrastructure (what am I saying??) and more shots at laughs given the pedigree of the actors. After 88 minutes, less was not more.
The title character is voiced with patent hip by Chris Rock, who brings life to a white blood cell/loose cannon cop on the trail of a particularly nasty baddy named Thrax (Lawrence Fishburne). Fishburne dips an octave or two below the tones of his "Matrix" alter ego and delivers real power as the virus out to destroy the "city" of Frank (Bill Murray), who is to hygiene and nutrition what Gary Condit is to truth and justice.
A cold capsule named Drix (David Hyde Pierce) and Frank's Mayor Phlegmming (William Shatner) likewise add to a cast that fairly clicks with hammish appeal, and the animation is top drawer, particularly when Thrax happens upon Frank's subconscious. What lacks is deeper imbedding into Frank's infrastructure (what am I saying??) and more shots at laughs given the pedigree of the actors. After 88 minutes, less was not more.
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