After their most passionate night of love making (which is ironic since Paul can't recall it) the Buchman's decide they want to start trying to have a baby.
While waiting at a bus stop, Paul & Jamie take a test in the Cosmopolitan magazine to see if they are compatible. Clips from previous episodes show how they met and their relationship developed.
Fran and Jamie have an interview with Lance Brockwell at City Hall. Paul is supposed to know him but cannot remember him. When he does, he visits Lance and it affects the job bid. Ira makes a bid on a store for expanding his business.
Paul & Jamie take Murray to a dog park to socialize with other dogs. Paul & Jamie meet the dog owners and find a new couple for double-dating. They offer show tickets to the couple when the tickets have already been offered to Fran and Ira.
Paul is scheduled to film the ball droppers in Times Square for New Years Eve, and Jamie going to the Mayor's ball. Everyone has plans, and they all change during the final minutes of the year.
Paul & Jamie are waiting for her ovulation date to have sex, to better the chances for creating a baby. When it does, things keep happening that them from being together. Debra, Paul's sister, reveals that she is gay and dating Joan.
While making love, Jamie throws out her back. While stuck on the floor, Paul runs her errands and tries to take his father to an eye doctor appointment. While at home, Jamie finds ways to get food, water, and keep herself entertained,.
Paul and Jamie each have strange dreams with sexual undertones and bizarre happenings. They try to interpret them, but even the interpretations are bizarre.
The Buchman's apartment alternates from sweltering hot to freezing cold. Paul & Jamie continue to try creating a baby and the sex is getting old. Paul & Jamie get irritated with each other. Ira starts gambling again and problems arise.
Paul & Jamie are upset that they are still not pregnant. Fran suggests checking into a fancy hotel for a relaxing, romantic evening. Mark suggests fertility enhancement procedures.
Ira dates a beautiful woman from the bakery. Paul shares the Splinky story from Ira's childhood. Jamie changes her hair and clothing to try something different. Her appearance causes different reactions. Paul thinks everyone hates him.
Through phone calls, Paul & Jamie talk to friends: Mark thinks Fran and Ira are still seeing each other; Ira has problems with his girlfriend; Fran is worried about Mark. Jamie says they are the glue that connects everyone.
Paul & Jamie take a sample of Paul's sperm to the hospital for testing, to see if he is the cause of their not being pregnant yet. They have less than an hour to get to the hospital, but everything seems to delay them.
Jamie goes to the hospital for a small diagnostic procedure with Fran's doctor. The doctor is very good looking. Ira pretends to be Paul's agent; Paul is fired from his job.
Paul makes a documentary about a weed while Jamie plans a weekend vacation in Pennsylvania. He does not want to leave until the film is finished. Jamie has problems with the mayor's campaign. Mark & Fran go on a weekend vacation.
Jamie plans shower for Lisa; Paul plans anniversary party for Sylvia & Burt, Fran gets back with Mark and quits her job. Paul tells Jamie he walked with a woman; Jamie tells Paul she kissed a co-worker. Paul walks out.